| USWorld

Larger text Larger text Smaller text Smaller text | Order Photo Reprints

Sealing artery to hunger hormone passes key test

Email Newsletters

Click here to sign up for one of our email newsletters.

Daily Photo Galleries

By Bloomberg News
Friday, March 8, 2013, 8:21 p.m.

Sealing off an artery that supplies blood to the portion of the stomach that produces the hunger- promoting hormone ghrelin reduced appetite and triggered weight loss in the first study of the approach in human volunteers.

The experiment involving five obese patients in Tbilisi, Georgia, found the procedure led to an average weight loss of 30 pounds within the first month and 45 pounds after six months, said lead researcher Nicholas Kipshidze. The results will be presented this weekend at the American College of Cardiology meeting in San Francisco.

The researchers threaded a catheter from an artery in the groin to the gastric artery, where they released tiny beads that blocked off blood flow to the stomach, Kipshidze said in a telephone interview. While the 30-minute procedure led to less weight loss than standard bariatric surgery, it wasn't as invasive and it is faster, he said. Three patients had stomach discomfort, though there were no other complications, he said.

“We are cutting off blood flow to the fundus of the stomach, which is known as the area where a lot of hormones are initiated,” said Kipshidze, who led the study when he was the physician-in-chief at Republican Hospital in Tbilisi. “I believe it may become a good alternative to bariatric surgery,” Kipshidze said. “Still, five patients is only five patients. I am cautiously optimistic.”

Subscribe today! Click here for our subscription offers.



Show commenting policy

Most-Read Nation

  1. Stocks up before earnings reports
  2. El Niño storms might not be savior for Calif.
  3. Half Moon Bay contest dubs 1,969-pound pumpkin the plumpest
  4. House’s Flores will seek speakership if Ryan doesn’t
  5. Supreme Court to consider reprieve for teens who kill
  6. Dissolving heart stent fuels hope for new generation of devices
  7. Community lines streets as students return to class in Roseburg
  8. Dell buying EMC in a transaction valued at about $67 billion
  9. Part of major highway reopens as South Carolina recovers from floods
  10. Army budget cuts stretch forces thin, threaten readiness, secretary says during conference
  11. Wyoming fire forces evacuations