Sealing artery to hunger hormone passes key test
Sealing off an artery that supplies blood to the portion of the stomach that produces the hunger- promoting hormone ghrelin reduced appetite and triggered weight loss in the first study of the approach in human volunteers.
The experiment involving five obese patients in Tbilisi, Georgia, found the procedure led to an average weight loss of 30 pounds within the first month and 45 pounds after six months, said lead researcher Nicholas Kipshidze. The results will be presented this weekend at the American College of Cardiology meeting in San Francisco.
The researchers threaded a catheter from an artery in the groin to the gastric artery, where they released tiny beads that blocked off blood flow to the stomach, Kipshidze said in a telephone interview. While the 30-minute procedure led to less weight loss than standard bariatric surgery, it wasn't as invasive and it is faster, he said. Three patients had stomach discomfort, though there were no other complications, he said.
“We are cutting off blood flow to the fundus of the stomach, which is known as the area where a lot of hormones are initiated,” said Kipshidze, who led the study when he was the physician-in-chief at Republican Hospital in Tbilisi. “I believe it may become a good alternative to bariatric surgery,” Kipshidze said. “Still, five patients is only five patients. I am cautiously optimistic.”
Show commenting policy
TribLive commenting policy
You are solely responsible for your comments and by using TribLive.com you agree to our Terms of Service.
We moderate comments. Our goal is to provide substantive commentary for a general readership. By screening submissions, we provide a space where readers can share intelligent and informed commentary that enhances the quality of our news and information.
While most comments will be posted if they are on-topic and not abusive, moderating decisions are subjective. We will make them as carefully and consistently as we can. Because of the volume of reader comments, we cannot review individual moderation decisions with readers.
We value thoughtful comments representing a range of views that make their point quickly and politely. We make an effort to protect discussions from repeated comments either by the same reader or different readers.
We follow the same standards for taste as the daily newspaper. A few things we won't tolerate: personal attacks, obscenity, vulgarity, profanity (including expletives and letters followed by dashes), commercial promotion, impersonations, incoherence, proselytizing and SHOUTING. Don't include URLs to Web sites.
We do not edit comments. They are either approved or deleted. We reserve the right to edit a comment that is quoted or excerpted in an article. In this case, we may fix spelling and punctuation.
We welcome strong opinions and criticism of our work, but we don't want comments to become bogged down with discussions of our policies and we will moderate accordingly.
We appreciate it when readers and people quoted in articles or blog posts point out errors of fact or emphasis and will investigate all assertions. But these suggestions should be sent via e-mail. To avoid distracting other readers, we won't publish comments that suggest a correction. Instead, corrections will be made in a blog post or in an article.
- Clinton: Women ‘expect’ extremism from terrorists, not GOP candidates
- Obama marks Hurricane Katrina anniversary in New Orleans visit
- Ex-crime lab chief: Illegal’s fatal shot in San Francisco likely accidental
- Bison gores worker on California’s Catalina Island
- US economy surged at 3.7 percent rate in April-June quarter
- Virginia reporter, cameraman killed on air; gunman also dies
- 8 Ashley Madison subscribers sue over release of info, seek class-action status
- Kraft Heinz recalls more than 2M pounds of turkey bacon
- Compatibility of 1st-responder radios in doubt
- Planned Parenthood alleges ‘smear’ campaign in letter to top lawmakers
- Department of Homeland Security gets more time for extended detention of migrant families awaiting asylum hearings