As I sit here scratching a mosquito bite, I’m suddenly interested in a recent question from a patient. Do vitamin B1 supplements repel mosquitos?

Here’s what I learned:

Mosquitos transmit several diseases, including malaria and West Nile virus. And they find their hosts (you and me) mostly by their sense of smell, say experts. Thus, most effective repellents work — not by killing mosquitos with chemicals — but by preventing them from wanting to come close to you in the first place.

Why do some people naturally attract mosquitos and others don’t? We all have natural chemistries that produce odors that are either attractive or repugnant to mosquitos. Pests are also drawn to sweet scents such as floral perfume, report some studies.

The theory with vitamin B1 (also known as thiamin) is that it changes the chemistry of the blood and alters one’s smell to make it less attractive to mosquitos.

But does it work?

A fascinating study in the Journal of Insect Science by researchers in the Department of Biology at New Mexico State University recruited brave volunteers to subject their hands to hungry mosquitos after using a variety of insect repellants (including a skin patch of vitamin B1). Here are their results:

Repellants with DEET (N,N-diethyl-meta-toluamide) reduced the attractiveness of the volunteers’ hands to mosquitos by the largest margin. Rather than killing them, DEET makes it hard for biting bugs to smell us, says the Environmental Protection Agency (EPA). It is safe for use on adults and children.

Of the non-DEET repellants tested, one with oil of lemon eucalyptus and p-menthane-3-8-diol (a chemical found in fruit that smells similar to menthol) also worked well to deter hungry mosquitos.

And what about the vitamin B1 patch? These scientists found that 300 milligrams of vitamin B1 transferred through the skin from a patch did not repel mosquitos. Other studies with vitamin B1 supplements taken orally have shown inconsistent results. Perhaps that’s because some people have more natural mosquito-repelling odors than others.

Researchers at NMSU did find one surprise, however. A perfume called Victoria Secret Bombshell (ingredients unknown) repelled mosquitos for more than 2 hours.

So, although vitamin B1 hasn’t been shown to be the most effective to repel mosquitos, it’s not likely to harm you if you try it. Excess amounts are excreted in the urine and there is currently no evidence that high doses of B1 taken orally are toxic.

So there you have it. Eat well. Live well. And use a reliable insect repellent.

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